Application Value of Liver and Spleen Stiffness Detected by Transient Elastography for Predicting Esophageal Varices









 中文 EN

ACADEMIC HISKY

MAFLD Assessment of liver health Viral hepatitis Liver Cancer and Cirrhosis Evaluate the efficacy of medication Others

Application Value of Liver and Spleen Stiffness Detected by Transient Elastography for Predicting Esophageal Varices

Yang Xueping. Chin J Ultra Med. 2017, 33(2)

Objective

•To investigate the utility of LSM and SSM for predicting HREV by transient elastography in CHB or HBV-related cirrhosis patients.

Methods

•LSM and SSM were detected by FibroTouch(FT) in 95 patients with CHB or HBV-related cirrhosis.
•Esophageal varices was observed by gastroscope.
•95 patients were divided into HREV(high-risk esophageal varices) and LREV(low-risk esophageal varices) group.
•The accuracy of variable for predicting HREV was evaluated by ROC curve and the results were compared.

Figures & Tables

Results

•There were 49 patients with HREV and 46 patients with LREV.
•LSM ≥ 17.6 kPa being the cut-off value, with an AUROC of 0.720, had an sensitivity (Se) of 61.2% specificity (Sp) of 76.1%, positive predictive value (PPV) of 73.2%, and negative predictive value (NPV) of 64.8% for predicting HREV.
•SSM ≥ 47.0 kPa with an AUROC of 0.893, had an Se of 85.7%, Sp of 87.0%, PPV of 87.5%, NPV of 85.1% for predicting HREV.
•SSM gave better diagnostic performance when compared with LSM(P < 0.05).

Conclusion

•SSM and LSM measured by FT can be used as a reliable noninvasive method to evaluate HREV in CHB or HBV related cirrhosis patients.
•The accuracy of SSM is better than that of LSM.

If you need more academic materials, please contact us.