•73 patients with cirrhosis.
•Child-Pugh classifications were obtained, portal vein widths were measured by Ultrasonic, liver and spleen stiffness were measured by FibroTouch.
•Electronic endoscopy, upper abdominal CT and serum relevant checks were obtained.
•The serum fibrosis markers APRI and AAR values were calculated.
•According to the results of gastroscopy, the patients were divided into A, B groups. Patients with severe esophageal and gastric varices (EV) who had high risk of bleeding were in group A; while patients without or with mild to moderate EV who had low risk of bleeding were in group B.
•Used t-test for continuous variables and 2 test for categorical variables to screen out variables different between groups and analyzed their correlation with severe EV and ROC curves. Then, Binary Logistic Regression was used to evaluate the performance of combined variables for diagnosing severe EV and their predictive value for the risk of bleeding.
•Only liver stiffness measurement (LSM), spleen stiffness measurement (SSM) and portal vein width (PVW) were significantly different between the two groups (P < 0.05).
•The cutoff values of LSM, SSM and PVW for diagnosing severe EV were respectively 23.4 kPa, 40.3 kPa and 11.5 mm. The AUROC were respectively 0.655, 0.788 and 0.709.
•The AUROC was 0.773 for LSM plus PVW and 0.840 for LSM plus PVW (with highest diagnostic performance).
•Better than liver stiffness, spleen stiffness, portal vein width and liver stiffness plus portal vein width, with good predictive value for esophageal and gastric varices bleeding.
