
•A total of 56 patients with malignant liver tumors who underwent surgical treatment were enrolled.
•The liver stiffness measurement (LSM) of the patients was determined by FibroTouch, and the relevant clinical data of the patients were collected. According to whether occurred postoperative complications grouped and compared. Multivariate analysis was performed on the factors that might influence postoperative complications.

•Univariate analysis showed that preoperative LSM, indocyanine green retention rate at 15 minutes (ICG R15), intraoperative blood loss, and Ishake score of liver fibrosis were the influencing factors of postoperative complications (P < 0.05).
•Multivariate logistic regression analysis showed that preoperative LSM and intraoperative blood loss were retained in the regression equation, suggesting that they were significant influencing factors for postoperative complications.
•ROC analysis showed that when the preoperative LSM was 24 kPa and the intraoperative blood loss was more than 350 ml, the sensitivity and specificity of predicting postoperative complications were the best, and the area under the ROC curve (AUC) was 0.794 and 0.719, respectively. If combined with intraoperative blood loss, the diagnostic efficiency can be significantly improved.