ACADEMIC HISKY
ACADEMIC HISKY
Analysis of risk factors and predictive value of surgical complications in patients underwent laparoscopic hepatectomy for hepatic malignancy
Li XJ, Feng XF, et al. China Journal of Endoscopy. 2019, 25 (12).
Objective
•To analyze the risk factors of surgical complications in patients underwent laparoscopic hepatectomy for hepatic malignancy, and explore the predictive value of relevant factors for postoperative complications.
Methods

•A total of 56 patients with malignant liver tumors who underwent surgical treatment were enrolled.
•The liver stiffness measurement (LSM) of the patients was determined by FibroTouch, and the relevant clinical data of the patients were collected. According to whether occurred postoperative complications grouped and compared. Multivariate analysis was performed on the factors that might influence postoperative complications.

Figures & Tables
Results

•Univariate analysis showed that preoperative LSM, indocyanine green retention rate at 15 minutes (ICG R15), intraoperative blood loss, and Ishake score of liver fibrosis were the influencing factors of postoperative complications (P < 0.05).
•Multivariate logistic regression analysis showed that preoperative LSM and intraoperative blood loss were retained in the regression equation, suggesting that they were significant influencing factors for postoperative complications.
•ROC analysis showed that when the preoperative LSM was 24 kPa and the intraoperative blood loss was more than 350 ml, the sensitivity and specificity of predicting postoperative complications were the best, and the area under the ROC curve (AUC) was 0.794 and 0.719, respectively. If combined with intraoperative blood loss, the diagnostic efficiency can be significantly improved.

Conclusion
•LSM has a high predictive value for the occurrence of complications after laparoscopic hepatectomy in patients with liver malignant tumors, and its combination with intraoperative blood loss has a higher predictive value.
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