LiY, Cao WF, et al. CHINESE ARCHIVES OF TRADITIONAL CHINESE MEDICINE. 2022:40(6).

•To observe the effect of Shenmai Lanling Decoction on liver fat content and liver fibrosis in patients with type 2 diabetes mellitus (T2DM) combined with non-alcoholic fatty liver disease (NAFLD).

•A total of 76 patients with T2DM and NAFLD were enrolled and randomly divided into two groups according to the ratio of 1:1, with 38 cases in each group.
•The control group was given diet control, avoid alcohol, exercise and other non-drug treatment and hypoglycemic, lipid-lowering and liver-protecting treatment. The observation group was treated with Shenmai Lanling decoction on the basis of the control group.

•The total effective rate of the observation group (92.11%, 35/38) was higher than that of the control group (71.05%, 27/38)(P < 0.05).
•After 8 and 12 weeks of treatment, the liver fat content, liver stiffness value and fat attenuation value in the observation group were lower than those in the control group (P < 0.05).

•Shenmai Lan-ling Decoction combined with metformin and atorvastatin in the treatment of T2DM combined with NAFLD is effective and can effectively reduce clinical symptoms,regulate cytokine levels,control blood sugar,improve liver function and reduce liver fat content and liver fibrosis.